Wallace Miller is investigating claims that the medication Dupixent may be linked to increased risk of cutaneous T-cell lymphoma (CTCL). Dupixent is the brand name for dupilumab, a prescription drug that can treat conditions including eczema (atopic dermatitis) and COPD.
If you or a loved one has been diagnosed with cutaneous T-cell lymphoma after using Dupixent, you may be eligible to file a lawsuit against the manufacturers. Reach out to our experienced attorneys at 331-425-8022 or fill out our online case evaluation for a free and confidential consultation.
Reviewed by David A. Neiman, Esq.
Image by Pixabay.
Timeline
October 2025 — Cases are beginning to be filed against the manufacturers of Dupixent alleging a connection between the medication and CTCL.
April 2025 — Research continues to support the link between Dupixent use and CTCL. A study in Frontiers in Oncology has identified a significant association between the use of the drug and the development of lymphoma.
August 2024 — A study published in the Journal of the American Academy of Dermatology provides additional support for the link between Dupixent use and diagnoses of CTCL.
January 2024 — A study published in Dermatologic Therapy finds that people who took Dupixent to treat atopic dermatitis had a higher risk of developing CTCL than those who did not.
July 2020 — A letter published in the Journal of the American Academy of Dermatology raised concerns that long-term use of Dupixent worsened cutaneous T-cell lymphoma.
2017 — Dupixent is approved by the FDA for the treatment of atopic dermatitis.
2007 — Pharmaceutical companies Sanofi and Regeneron begin working together to develop therapeutic antibodies.
What is Dupixent?
Dupixent, the brand name for dupilumab, is an injectable drug first developed in 2017 by Regeneron Pharmaceuticals and Sanofi Biotechnology. Available in pen and syringe forms, Dupixent injections are prescribed to treat:
- Eczema, also known as atopic dermatitis (AD)
- Asthma patients
- Chronic obstructive pulmonary disease (COPD)
- Chronic rhinosinusitis with nasal polyps
- Eosinophilic esophagitis
- Prurigo nodularis
- Chronic spontaneous urticaria
- Bullous pemphigoid
According to the drug manufacturers, Dupixent is used by about one million patients worldwide. Since its launch, the drug has grossed more than $30 billion in total global sales.
The link between Dupixent use and cutaneous t-cell lymphoma (CTCL)
The development of Dupixent was a significant breakthrough in treating conditions like eczema, COPD, and eosinophilic esophagitis. However, a growing body of scientific research has found an association between the use of dupilumab and cutaneous T-cell lymphoma (CTCL).
Concerns over CTCL and Dupixent use were first raised in 2020 in a letter published in the Journal of the American Academy of Dermatology. Since then, numerous studies have been conducted on the relationship between dupilumab and the development of cutaneous T-cell lymphoma.
A study published in April 2024 found that people who had been treated with dupilumab for atopic dermatitis were more than four times more likely to be diagnosed with CTCL than those who were not. Additional research in 2025 has supported these conclusions and underscored the link between Dupixent and CTCL.
What is CTCL?
Cutaneous T-cell lymphoma (CTCL) is a rare but aggressive form of skin cancer. It affects white blood cells called T-cells, which help the body’s immune system fight germs. A type of non-Hodgkin lymphoma, it can cause a rash, scaly patches on the skin, and sometimes other growths.
The causes of CTCL are not fully understood. However, some people may be more likely to develop the condition, including:
- Older people, especially those over age 50.
- People assigned male at birth.
- Black people.
- People with immune system issues, including HIV/AIDS.
- People with a family history of lymphoma or other cancers.
- People who have been exposed to certain chemicals or toxic substances.
Image by Pixabay.
CTCL symptoms and treatments
There are two types of cutaneous T-cell lymphoma: mycosis fungoides and Sezary syndrome. Mycosis fungoides is the most common type and grows slowly, mainly impacting the skin. Sezary syndrome is less common and affects the blood as well as the skin.
Symptoms of both types of CTCL include:
- Patches of raised, scaly skin that may be itchy
- Patches that are red, pink, brown, gray, or lighter than the surrounding skin
- Lumps on the skin that may break open
- Swollen lymph nodes
- Hair loss
- Thickened skin on palms and soles
- A scaly, itchy rash
While treatment for cutaneous T-cell lymphoma depends on the type of skin cancer, it may include skin creams, light therapy, chemotherapy, and radiation therapy.
The drug companies behind Dupixent
In 2007, Sanofi and Regeneron Pharmaceuticals partnered to develop therapeutic antibodies for conditions including arthritis and eczema. Sanofi, then Sanofi-Aventis, is a French company whose American arm markets Dupixent in the U.S. Founded in 1988, Regeneron Pharmaceuticals is a publicly traded biotechnology company based in New York that develops medications for people with serious diseases.
We are in the early stages of investigation into the connections between Dupixent and CTCL. As research continues, these companies and others involved in the manufacturing of Dupixent may be held liable for failing to warn patients about its potential dangers.
Do I qualify for a potential Dupixent lawsuit?
If you or a loved one used Dupixent and developed cutaneous T-cell lymphoma (CTCL), you may be eligible to participate in a future Dupixent lawsuit.
You may have a claim against the manufacturers of Dupixent if you:
- Used Dupixent for eczema (also known as atopic dermatitis), asthma, COPD, or another condition;
- Used Dupixent for a prolonged period of time;
- Used the pen or syringe form of the injectable drug; and
- Were diagnosed with CTCL after prolonged usage of the drug.
Wallace Miller partner David A. Neiman.
Contact Wallace Miller
The team of attorneys and legal professionals at Wallace Miller is dedicated to protecting the rights of individuals who have been harmed by dangerous drugs. Our lawyers have more than 160 years of cumulative experience fighting against some of the largest corporations in the world to achieve fair compensation for our clients.
The manufacturers of Dupixent claimed that it was a breakthrough drug for eczema, COPD, asthma, and other serious health conditions. Now, a growing number of studies are showing that the medication is causing skin cancer in those who use it. If you have been diagnosed with cutaneous T-cell lymphoma after Dupixent use, talk to our legal team. We are available to discuss your options free of charge at 331-425-8022 or via our online case evaluation.